MYO15A and USP13

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MYO15A	USP13
Description		myosin XVA	ubiquitin specific peptidase 13
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GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Myosin Complex Vesicle Stereocilium Extracellular Exosome Actin-based Cell Projection	Nucleus Nucleoplasm Cytosol
	Molecular Function	Microfilament Motor Activity Calmodulin Binding ATP Binding Actin-dependent ATPase Activity Actin Filament Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Actin Filament Organization Sensory Perception Of Sound Vesicle Transport Along Actin Filament	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Population Proliferation Regulation Of Autophagy Protein Deubiquitination Protein Phosphopantetheinylation Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways			Ub-specific processing proteases Regulation of PTEN stability and activity
Drugs
Diseases		Deafness, autosomal recessive
GWAS		Change in neurofilament light levels ( 31295725) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Red blood cell count ( 32888494) Schizophrenia ( 25056061) Serum folate levels ( 29953918)
Interacting Genes		4 interacting genes: EPS8 FASLG USP13 WHRN	18 interacting genes: AMFR BAG6 DAZAP2 DVL1 FNBP1L FUNDC2 LAPTM5 MCL1 MDC1 MRPL20 MYO15A SIAH2 SPRR2C TRIM55 TRIM63 UBC UBL4A UIMC1
Entrez ID		51168	8975
HPRD ID		04049	04666
Ensembl ID		ENSG00000091536	ENSG00000058056
Uniprot IDs		Q9UKN7	A0A0A6YZ17 Q92995
PDB IDs		6KZ1	2L80 2LBC
Enriched GO Terms of Interacting Partners?
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