WHRN and MYO15A

Data Source:
HPRD (in vitro, in vivo)

		WHRN	MYO15A
Description		whirlin	myosin XVA
Image
GO Annotations	Cellular Component	Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Actin Filament Plasma Membrane Growth Cone Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Ciliary Basal Body Neuronal Cell Body Synapse Periciliary Membrane Compartment USH2 Complex	Cytoplasm Actin Cytoskeleton Myosin Complex Vesicle Stereocilium Extracellular Exosome Actin-based Cell Projection
	Molecular Function	Protein Binding Identical Protein Binding	Microfilament Motor Activity Calmodulin Binding ATP Binding Actin-dependent ATPase Activity Actin Filament Binding
	Biological Process	Retina Homeostasis Sensory Perception Of Sound Positive Regulation Of Gene Expression Cerebellar Purkinje Cell Layer Formation Establishment Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Sensory Perception Of Light Stimulus Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Stereocilium Organization Paranodal Junction Maintenance	Actin Filament Organization Sensory Perception Of Sound Vesicle Transport Along Actin Filament
Pathways
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal recessive	Deafness, autosomal recessive
GWAS			Change in neurofilament light levels ( 31295725) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Red blood cell count ( 32888494) Schizophrenia ( 25056061) Serum folate levels ( 29953918)
Interacting Genes		17 interacting genes: BEND7 BMI1 CASK COL17A1 EFHC1 GOLGA2 GPSM2 HEMGN KEAP1 LRP4 LRRC4C MYO15A MYO7A PXN RPS6KA1 SPC24 TPRN	4 interacting genes: EPS8 FASLG USP13 WHRN
Entrez ID		25861	51168
HPRD ID		09718	04049
Ensembl ID		ENSG00000095397	ENSG00000091536
Uniprot IDs		B9EGE6 Q9P202	Q9UKN7
PDB IDs		1UEZ 1UF1 1UFX 6KZ1	6KZ1
Enriched GO Terms of Interacting Partners?
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