WHRN and LRP4

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WHRN	LRP4
Description		whirlin	LDL receptor related protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Actin Filament Plasma Membrane Growth Cone Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Ciliary Basal Body Neuronal Cell Body Synapse Periciliary Membrane Compartment USH2 Complex	Plasma Membrane Cell Surface Postsynaptic Density Integral Component Of Membrane Dendrite Neuromuscular Junction Neuronal Cell Body Plasma Membrane Raft Synaptic Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Calcium Ion Binding Protein Binding Receptor Tyrosine Kinase Binding Apolipoprotein Binding Protein Homodimerization Activity Scaffold Protein Binding
	Biological Process	Retina Homeostasis Sensory Perception Of Sound Positive Regulation Of Gene Expression Cerebellar Purkinje Cell Layer Formation Establishment Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Sensory Perception Of Light Stimulus Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Stereocilium Organization Paranodal Junction Maintenance	Kidney Development Hair Follicle Development Endocytosis Dorsal/ventral Pattern Formation Proximal/distal Pattern Formation Wnt Signaling Pathway Negative Regulation Of Ossification Odontogenesis Of Dentin-containing Tooth Embryonic Digit Morphogenesis Dendrite Morphogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Axonogenesis Synapse Organization Synaptic Growth At Neuromuscular Junction Limb Development Skeletal Muscle Acetylcholine-gated Channel Clustering Negative Regulation Of Canonical Wnt Signaling Pathway Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Amyloid-beta Clearance By Cellular Catabolic Process Positive Regulation Of Presynaptic Membrane Organization Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways			ECM proteoglycans
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal recessive	Cenani-Lenz syndactyly syndrome
GWAS			Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Bone mineral density (hip) ( 19079262) D-dimer levels ( 21502573) General risk tolerance (MTAG) ( 30643258) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 28334899) Heel bone mineral density ( 30598549 28869591) Intraocular pressure ( 29617998) Mood instability ( 31168069) Pre-treatment viral load in HIV-1 infection ( 31219150) Reaction time ( 29844566) Systolic blood pressure ( 30224653) Urate levels ( 31578528) Venous thromboembolism ( 31420334)
Interacting Genes		17 interacting genes: BEND7 BMI1 CASK COL17A1 EFHC1 GOLGA2 GPSM2 HEMGN KEAP1 LRP4 LRRC4C MYO15A MYO7A PXN RPS6KA1 SPC24 TPRN	1 interacting genes: WHRN
Entrez ID		25861	4038
HPRD ID		09718	18517
Ensembl ID		ENSG00000095397	ENSG00000134569
Uniprot IDs		B9EGE6 Q9P202	O75096
PDB IDs		1UEZ 1UF1 1UFX 6KZ1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?