NPY and MEP1B

Data Source:
HPRD (in vitro)

		NPY	MEP1B
Description		neuropeptide Y	meprin A subunit beta
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Synapse Neuronal Dense Core Vesicle	Extracellular Region Integral Component Of Plasma Membrane Meprin A Complex
	Molecular Function	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Signaling Receptor Binding Hormone Activity Neuropeptide Hormone Activity Calcium Channel Regulator Activity Protein Binding Neuropeptide Y Receptor Binding	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding Identical Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Chemical Synaptic Transmission Feeding Behavior Regulation Of Blood Pressure Adult Feeding Behavior Central Nervous System Neuron Development Cerebral Cortex Development Neuron Projection Development Positive Regulation Of Appetite Intestinal Epithelial Cell Differentiation	Proteolysis Inflammatory Response Toxin Transport
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs		Phentermine 2-aminoisobutyric acid L-tyrosinamide
Diseases
GWAS		Adult body size ( 32376654) Aggressive periodontitis (sex interaction) ( 25256105) Body size at age 10 ( 32376654) Chronotype ( 30696823) Morning person ( 30696823) Periodontitis ( 23459936) Vitamin D levels ( 25208829)	Metabolite levels ( 23823483) TRAIL levels ( 27989323)
Interacting Genes		16 interacting genes: ATP12A BAG6 GHRL MC4R MEP1A MEP1B NPFF NPFFR2 NPY1R NPY2R NPY4R NPY5R NR1H2 PMCH UBQLN1 UBQLN2	12 interacting genes: CCK FN1 GAST GCG GRP MEP1A NPY OS9 PRKACA PRKCD PYY SCT
Entrez ID		4852	4225
HPRD ID		01214	02667
Ensembl ID		ENSG00000122585	ENSG00000141434
Uniprot IDs		A4D158 P01303	J3QKX5 Q16820
PDB IDs		1QFA 1RON	4GWM 4GWN
Enriched GO Terms of Interacting Partners?
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