NPY and NPY4R

Data Source:
HPRD (in vitro)

		NPY	NPY4R
Description		neuropeptide Y	neuropeptide Y receptor Y4
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Synapse Neuronal Dense Core Vesicle
	Molecular Function	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Signaling Receptor Binding Hormone Activity Neuropeptide Hormone Activity Calcium Channel Regulator Activity Protein Binding Neuropeptide Y Receptor Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Chemical Synaptic Transmission Feeding Behavior Regulation Of Blood Pressure Adult Feeding Behavior Central Nervous System Neuron Development Cerebral Cortex Development Neuron Projection Development Positive Regulation Of Appetite Intestinal Epithelial Cell Differentiation
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Phentermine 2-aminoisobutyric acid L-tyrosinamide	Peptide YY (3-36) Obinepitide TM30339
Diseases
GWAS		Adult body size ( 32376654) Aggressive periodontitis (sex interaction) ( 25256105) Body size at age 10 ( 32376654) Chronotype ( 30696823) Morning person ( 30696823) Periodontitis ( 23459936) Vitamin D levels ( 25208829)
Interacting Genes		16 interacting genes: ATP12A BAG6 GHRL MC4R MEP1A MEP1B NPFF NPFFR2 NPY1R NPY2R NPY4R NPY5R NR1H2 PMCH UBQLN1 UBQLN2	3 interacting genes: NPY PPY PYY
Entrez ID		4852	5540
HPRD ID		01214	03476
Ensembl ID		ENSG00000122585	ENSG00000204174
Uniprot IDs		A4D158 P01303	P50391
PDB IDs		1QFA 1RON	2IK5
Enriched GO Terms of Interacting Partners?
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