MEP1B and CCK

Data Source:
HPRD (in vitro)

		MEP1B	CCK
Description		meprin A subunit beta	cholecystokinin
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Integral Component Of Plasma Membrane Meprin A Complex	Extracellular Region Extracellular Space Axon Dendrite Axon Initial Segment Terminal Bouton Axon Hillock Perikaryon
	Molecular Function	Metalloendopeptidase Activity Protein Binding Zinc Ion Binding Identical Protein Binding	Hormone Activity Neuropeptide Hormone Activity Protein Binding Peptide Hormone Receptor Binding
	Biological Process	Proteolysis Inflammatory Response Toxin Transport	Neuron Migration Release Of Cytochrome C From Mitochondria Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Digestion Memory Positive Regulation Of Cell Population Proliferation Visual Learning Positive Regulation Of Glutamate Secretion Positive Regulation Of Protein-containing Complex Assembly Negative Regulation Of Appetite Eating Behavior Positive Regulation Of Apoptotic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Eating Behavior Positive Regulation Of Sensory Perception Of Pain Negative Regulation Of Behavioral Fear Response Positive Regulation Of Behavioral Fear Response
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			Camostat
Diseases
GWAS		Metabolite levels ( 23823483) TRAIL levels ( 27989323)	Adult body size ( 32376654) Body mass index ( 24348519 28892062 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (SNP x SNP interaction) ( 22344221) Body size at age 10 ( 32376654) Night sleep phenotypes ( 27126917)
Interacting Genes		12 interacting genes: CCK FN1 GAST GCG GRP MEP1A NPY OS9 PRKACA PRKCD PYY SCT	7 interacting genes: CCKAR CCKBR CPE ENPEP MEP1A MEP1B UBQLN2
Entrez ID		4225	885
HPRD ID		02667	00321
Ensembl ID		ENSG00000141434	ENSG00000187094
Uniprot IDs		J3QKX5 Q16820	P06307 Q6FG82
PDB IDs		4GWM 4GWN
Enriched GO Terms of Interacting Partners?
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