LMNB1 and TOR1AIP1

Data Source:
HPRD (in vivo)

		LMNB1	TOR1AIP1
Description		lamin B1	torsin 1A interacting protein 1
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Lamin Filament Nucleoplasm Membrane Nuclear Matrix Nuclear Membrane	Nucleus Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Phospholipase Binding Sequence-specific Double-stranded DNA Binding	ATPase Activator Activity Protein Binding Cytoskeletal Protein Binding ATPase Binding
	Biological Process	Interleukin-12-mediated Signaling Pathway	Positive Regulation Of ATPase Activity Protein Localization To Nucleus Membrane Organization Nuclear Membrane Organization
Pathways		Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body fat percentage ( 31752434) Parkinson's disease (motor and cognition) ( 22658654)	Refractive error ( 32231278)
Interacting Genes		44 interacting genes: ABCG8 ATF4 CASP3 CASP6 CCDC88B CDK1 CENPH DMAP1 FAM169A GABARAP GIT2 GZMA GZMB KPNA1 KPNA5 KPNA6 LBR LMNA LMNB2 M1AP MAP1LC3A MAP1LC3C MBIP MELK PIAS2 PIH1D2 PLEC PPP1R13B PRKCA PRKCB PRKCD PRPH PTEN RNF123 SERPINA3 SNAPIN SRPK2 SUMO4 TMPO TOR1AIP1 TP53BP2 UBE2I URB2 YWHAQ	7 interacting genes: CDC42 LMNA LMNB1 PPP1CA PPP1CC TERF2 TERF2IP
Entrez ID		4001	26092
HPRD ID		01036	13958
Ensembl ID		ENSG00000113368	ENSG00000143337
Uniprot IDs		B4DZT3 P20700	Q5JTV8
PDB IDs		2KPW 3JT0 3TYY 3UMN 5VVX	4TVS
Enriched GO Terms of Interacting Partners?
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