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LMNB1 and GZMA
Data Source:
HPRD
(in vitro, in vivo)
LMNB1
GZMA
Description
lamin B1
granzyme A
Image
GO Annotations
Cellular Component
Nucleus
Nuclear Envelope
Nuclear Inner Membrane
Lamin Filament
Nucleoplasm
Membrane
Nuclear Matrix
Nuclear Membrane
Immunological Synapse
Extracellular Region
Nucleus
Molecular Function
Structural Molecule Activity
Protein Binding
Phospholipase Binding
Sequence-specific Double-stranded DNA Binding
Serine-type Endopeptidase Activity
Protein Binding
Protein Homodimerization Activity
Biological Process
Interleukin-12-mediated Signaling Pathway
Apoptotic Process
Immune Response
Response To Bacterium
Cytolysis
Negative Regulation Of Endodeoxyribonuclease Activity
Positive Regulation Of Apoptotic Process
Negative Regulation Of DNA Binding
Negative Regulation Of Oxidoreductase Activity
Proteolysis Involved In Cellular Protein Catabolic Process
Pyroptosis
Granzyme-mediated Programmed Cell Death Signaling Pathway
Cytotoxic T Cell Pyroptotic Process
Pathways
Meiotic synapsis
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Nuclear Envelope Breakdown
Initiation of Nuclear Envelope (NE) Reformation
Breakdown of the nuclear lamina
Depolymerisation of the Nuclear Lamina
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
Body fat percentage (
31752434
)
Parkinson's disease (motor and cognition) (
22658654
)
Interacting Genes
44 interacting genes:
ABCG8
ATF4
CASP3
CASP6
CCDC88B
CDK1
CENPH
DMAP1
FAM169A
GABARAP
GIT2
GZMA
GZMB
KPNA1
KPNA5
KPNA6
LBR
LMNA
LMNB2
M1AP
MAP1LC3A
MAP1LC3C
MBIP
MELK
PIAS2
PIH1D2
PLEC
PPP1R13B
PRKCA
PRKCB
PRKCD
PRPH
PTEN
RNF123
SERPINA3
SNAPIN
SRPK2
SUMO4
TMPO
TOR1AIP1
TP53BP2
UBE2I
URB2
YWHAQ
17 interacting genes:
ACTG1
APEX1
GOLGA2
H1-1
H2BC21
HDC
HMGB2
HNRNPK
HSP90AA1
HSPA4
LMNA
LMNB1
NCL
NDUFS3
SET
XRCC5
XRCC6
Entrez ID
4001
3001
HPRD ID
01036
00771
Ensembl ID
ENSG00000113368
ENSG00000145649
Uniprot IDs
B4DZT3
P20700
P12544
PDB IDs
2KPW
3JT0
3TYY
3UMN
5VVX
1HF1
1OP8
1ORF
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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