TOR1AIP1 and LMNB1

Data Source:
HPRD (in vivo)

		TOR1AIP1	LMNB1
Description		torsin 1A interacting protein 1	lamin B1
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GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Nucleus Nuclear Envelope Nuclear Inner Membrane Lamin Filament Nucleoplasm Membrane Nuclear Matrix Nuclear Membrane
	Molecular Function	ATPase Activator Activity Protein Binding Cytoskeletal Protein Binding ATPase Binding	Structural Molecule Activity Protein Binding Phospholipase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of ATPase Activity Protein Localization To Nucleus Membrane Organization Nuclear Membrane Organization	Interleukin-12-mediated Signaling Pathway
Pathways			Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Blood protein levels ( 30072576 29875488) Body fat percentage ( 31752434) Parkinson's disease (motor and cognition) ( 22658654)
Interacting Genes		7 interacting genes: CDC42 LMNA LMNB1 PPP1CA PPP1CC TERF2 TERF2IP	44 interacting genes: ABCG8 ATF4 CASP3 CASP6 CCDC88B CDK1 CENPH DMAP1 FAM169A GABARAP GIT2 GZMA GZMB KPNA1 KPNA5 KPNA6 LBR LMNA LMNB2 M1AP MAP1LC3A MAP1LC3C MBIP MELK PIAS2 PIH1D2 PLEC PPP1R13B PRKCA PRKCB PRKCD PRPH PTEN RNF123 SERPINA3 SNAPIN SRPK2 SUMO4 TMPO TOR1AIP1 TP53BP2 UBE2I URB2 YWHAQ
Entrez ID		26092	4001
HPRD ID		13958	01036
Ensembl ID		ENSG00000143337	ENSG00000113368
Uniprot IDs		Q5JTV8	B4DZT3 P20700
PDB IDs		4TVS	2KPW 3JT0 3TYY 3UMN 5VVX
Enriched GO Terms of Interacting Partners?
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