ITGB7 and MADCAM1

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		ITGB7	MADCAM1
Description		integrin subunit beta 7	mucosal vascular addressin cell adhesion molecule 1
Image
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Membrane Integrin Alpha4-beta7 Complex Receptor Complex Extracellular Exosome	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity Metal Ion Binding Cell Adhesion Molecule Binding	Integrin Binding Involved In Cell-matrix Adhesion
	Biological Process	Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Cell Migration Extracellular Matrix Organization Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Receptor Clustering Viral Entry Into Host Cell Regulation Of Immune Response Leukocyte Tethering Or Rolling T Cell Migration	Positive Regulation Of Leukocyte Migration Immune Response Cell Adhesion Cell-matrix Adhesion Signal Transduction Integrin-mediated Signaling Pathway Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Receptor Clustering Regulation Of Immune Response Leukocyte Tethering Or Rolling Positive Regulation Of Lymphocyte Migration
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions
Drugs		R1295 Vedolizumab
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		15 interacting genes: CDH1 DAB1 DOK1 EED FLNA FN1 ITGA4 ITGAE MADCAM1 PRKCB PRKCD RACK1 TLN1 TNS2 VCAM1	3 interacting genes: CD44 ITGA4 ITGB7
Entrez ID		3695	8174
HPRD ID		00948	00035
Ensembl ID		ENSG00000139626	ENSG00000099866
Uniprot IDs		P26010	Q13477
PDB IDs		2BRQ 3V4P 3V4V	1BQS 1GSM 4HBQ 4HC1 4HCR 4HD9
Enriched GO Terms of Interacting Partners?
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