ITGB7 and ITGAE

Data Source:
HPRD (in vivo)

		ITGB7	ITGAE
Description		integrin subunit beta 7	integrin subunit alpha E
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Membrane Integrin Alpha4-beta7 Complex Receptor Complex Extracellular Exosome	Plasma Membrane Integrin Complex External Side Of Plasma Membrane
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity Metal Ion Binding Cell Adhesion Molecule Binding	Metal Ion Binding
	Biological Process	Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Cell Migration Extracellular Matrix Organization Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Receptor Clustering Viral Entry Into Host Cell Regulation Of Immune Response Leukocyte Tethering Or Rolling T Cell Migration	Cell Adhesion Integrin-mediated Signaling Pathway Extracellular Matrix Organization
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions	Integrin cell surface interactions
Drugs		R1295 Vedolizumab
Diseases
GWAS		Obesity-related traits ( 23251661)	Attention deficit hyperactivity disorder ( 18839057)
Interacting Genes		15 interacting genes: CDH1 DAB1 DOK1 EED FLNA FN1 ITGA4 ITGAE MADCAM1 PRKCB PRKCD RACK1 TLN1 TNS2 VCAM1	5 interacting genes: CDH1 CHFR EED ITGB7 TRIM54
Entrez ID		3695	3682
HPRD ID		00948	05249
Ensembl ID		ENSG00000139626	ENSG00000083457
Uniprot IDs		P26010	P38570
PDB IDs		2BRQ 3V4P 3V4V
Enriched GO Terms of Interacting Partners?
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