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ILK and LIMS1
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
ILK
LIMS1
Description
integrin linked kinase
LIM zinc finger domain containing 1
Image
GO Annotations
Cellular Component
Stress Fiber
Nucleoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Sarcomere
Lamellipodium
Cytoplasm
Cytosol
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Protein-containing Complex Binding
Biological Process
Cell Morphogenesis
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Positive Regulation Of Signal Transduction
Tumor Necrosis Factor-mediated Signaling Pathway
Cell Junction Assembly
Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Phosphorylation
Positive Regulation Of Transcription, DNA-templated
Platelet Aggregation
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of NIK/NF-kappaB Signaling
Epithelial To Mesenchymal Transition
Cell Aging
Positive Regulation Of Gene Expression
Positive Regulation Of Cell-substrate Adhesion
Tumor Necrosis Factor-mediated Signaling Pathway
Cell Junction Assembly
Positive Regulation Of GTPase Activity
Establishment Of Protein Localization
Cell-cell Junction Organization
Negative Regulation Of Transcription, DNA-templated
Regulation Of Epithelial Cell Proliferation
Positive Regulation Of Focal Adhesion Assembly
Cellular Response To Transforming Growth Factor Beta Stimulus
Cell-cell Adhesion
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
Cell-extracellular matrix interactions
Cell-extracellular matrix interactions
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS
Malaria (
31844061
)
Apolipoprotein B levels (
32203549
)
Beard thickness (
26926045
)
Birth weight (
31043758
)
Excessive hairiness (
29895819
)
Eyebrow thickness (
26926045
)
Immature fraction of reticulocytes (
32888494
)
LDL cholesterol (
30275531
)
LDL cholesterol levels (
32203549
)
Monobrow thickness (
26926045
)
Scalp hair shape (
26926045
)
Interacting Genes
42 interacting genes:
AKT1
CASP8
CASP9
CAV1
CKB
FERMT1
FERMT2
FERMT3
GSK3B
ILKAP
ITGB1
ITGB2
ITGB3
LIMS1
LIMS2
MATK
MBP
MIPEP
NCK2
NOTCH1
PARVA
PARVB
PARVG
PDPK1
PPP1R12A
PTPN11
PXN
RICTOR
RNF19A
RPL13
SERPINA4
SHC1
SNRNP35
SUMO2
TMSB4X
TRIM27
TWF2
ZBTB48
ZNF133
ZNF205
ZNF579
ZNF746
47 interacting genes:
ADAMTS9
ATXN10
CATSPER1
CCN2
COL8A1
CSRP3
CWF19L2
DAPK1
EHMT2
FAM90A1
FERMT2
FERMT3
FMR1
GEM
ILK
INO80B
IPO7
KPRP
LMO3
LPXN
MBIP
MYO15B
NCK2
NEB
OSR2
PARVA
PEG3
PLCE1
RAD51D
RBBP8
RSU1
SCNM1
SMURF1
TBC1D22B
TCEA2
TGFBR1
TMSB4X
TRIO
TTN
USP11
ZIM2
ZMYM4
ZNF160
ZNF410
ZNF417
ZNF564
ZNF587
Entrez ID
3611
3987
HPRD ID
03842
03978
Ensembl ID
ENSG00000166333
ENSG00000169756
Uniprot IDs
Q13418
V9HWF0
P48059
PDB IDs
2KBX
3F6Q
3IXE
3KMU
3KMW
3REP
4HI8
4HI9
6MIB
1G47
1NYP
1U5S
2COR
2D8X
2KBX
3F6Q
4HI8
4HI9
6MIF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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