LIMS1 and PEG3

Data Source:
BioGRID (two hybrid)

		LIMS1	PEG3
Description		LIM zinc finger domain containing 1	paternally expressed 3
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Protein-containing Complex Perinuclear Region Of Cytoplasm	Nucleus Autophagosome
	Molecular Function	Protein Binding Zinc Ion Binding Protein Kinase Binding Protein-containing Complex Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Molecular_function Metal Ion Binding
	Biological Process	Epithelial To Mesenchymal Transition Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Tumor Necrosis Factor-mediated Signaling Pathway Cell Junction Assembly Positive Regulation Of GTPase Activity Establishment Of Protein Localization Cell-cell Junction Organization Negative Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Proliferation Positive Regulation Of Focal Adhesion Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Cell-cell Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Integrin-mediated Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Apoptotic Process Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Beard thickness ( 26926045) Birth weight ( 31043758) Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045)	Urate levels in lean individuals ( 25811787)
Interacting Genes		47 interacting genes: ADAMTS9 ATXN10 CATSPER1 CCN2 COL8A1 CSRP3 CWF19L2 DAPK1 EHMT2 FAM90A1 FERMT2 FERMT3 FMR1 GEM ILK INO80B IPO7 KPRP LMO3 LPXN MBIP MYO15B NCK2 NEB OSR2 PARVA PEG3 PLCE1 RAD51D RBBP8 RSU1 SCNM1 SMURF1 TBC1D22B TCEA2 TGFBR1 TMSB4X TRIO TTN USP11 ZIM2 ZMYM4 ZNF160 ZNF410 ZNF417 ZNF564 ZNF587	6 interacting genes: BRCA1 LIMS1 SIAH1 SIAH2 TRAF2 USP7
Entrez ID		3987	5178
HPRD ID		03978	03285
Ensembl ID		ENSG00000169756	ENSG00000198300
Uniprot IDs		P48059	Q96Q96 Q9GZU2
PDB IDs		1G47 1NYP 1U5S 2COR 2D8X 2KBX 3F6Q 4HI8 4HI9 6MIF	4BHX
Enriched GO Terms of Interacting Partners?
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