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ILK and MIPEP
Data Source:
BioGRID
(two hybrid)
ILK
MIPEP
Description
integrin linked kinase
mitochondrial intermediate peptidase
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Nucleoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Sarcomere
Lamellipodium
Mitochondrion
Mitochondrial Matrix
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein Kinase Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Metalloendopeptidase Activity
Metal Ion Binding
Biological Process
Cell Morphogenesis
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Positive Regulation Of Signal Transduction
Tumor Necrosis Factor-mediated Signaling Pathway
Cell Junction Assembly
Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Phosphorylation
Positive Regulation Of Transcription, DNA-templated
Platelet Aggregation
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of NIK/NF-kappaB Signaling
Proteolysis
Peptide Metabolic Process
Protein Processing Involved In Protein Targeting To Mitochondrion
Pathways
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Malaria (
31844061
)
Fourth ventricle volume (
31530798
)
Lung cancer (
21725308
)
Myopia (pathological) (
21640322
)
Venous thromboembolism (
32232851
)
Visceral adipose tissue adjusted for BMI (
22589738
)
Interacting Genes
42 interacting genes:
AKT1
CASP8
CASP9
CAV1
CKB
FERMT1
FERMT2
FERMT3
GSK3B
ILKAP
ITGB1
ITGB2
ITGB3
LIMS1
LIMS2
MATK
MBP
MIPEP
NCK2
NOTCH1
PARVA
PARVB
PARVG
PDPK1
PPP1R12A
PTPN11
PXN
RICTOR
RNF19A
RPL13
SERPINA4
SHC1
SNRNP35
SUMO2
TMSB4X
TRIM27
TWF2
ZBTB48
ZNF133
ZNF205
ZNF579
ZNF746
2 interacting genes:
ILK
MAPK6
Entrez ID
3611
4285
HPRD ID
03842
03761
Ensembl ID
ENSG00000166333
ENSG00000027001
Uniprot IDs
Q13418
V9HWF0
Q99797
PDB IDs
2KBX
3F6Q
3IXE
3KMU
3KMW
3REP
4HI8
4HI9
6MIB
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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