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HSD17B13 and CLDN19
Data Source:
BioGRID
(two hybrid)
HSD17B13
CLDN19
Description
hydroxysteroid 17-beta dehydrogenase 13
claudin 19
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Lipid Droplet
Cytosol
Nucleus
Plasma Membrane
Bicellular Tight Junction
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Junction Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Molecular_function
Protein Binding
Steroid Dehydrogenase Activity
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Structural Molecule Activity
Identical Protein Binding
Biological Process
Lipid Droplet Organization
Positive Regulation Of Lipid Biosynthetic Process
Positive Regulation Of Protein Phosphorylation
Cell Adhesion
Visual Perception
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Neuronal Action Potential Propagation
Negative Regulation Of Cell Migration
Actin Cytoskeleton Reorganization
Response To Stimulus
Negative Regulation Of Wound Healing
Bicellular Tight Junction Assembly
Regulation Of Transepithelial Transport
Positive Regulation Of Cell Junction Assembly
Pathways
Lipid particle organization
Tight junction interactions
Drugs
Diseases
GWAS
Bulimia nervosa (
23568457
)
Liver enzyme levels (alanine transaminase) (
22001757
)
Nonalcoholic steatohepatitis (
32298765
)
Platelet count (
22139419
)
Rosacea symptom severity (
29771307
)
Triglyceride levels (
31928498
)
Interacting Genes
118 interacting genes:
ABHD16A
ADGRE2
AGPAT3
AGPAT4
AGTRAP
AIG1
ANKRD46
AOC3
APOA2
ARL6IP1
ATP6V0C
BBC3
BRICD5
C3orf52
CACNG1
CALHM6
CCDC167
CDIPT
CLDN10
CLDN19
CLDN4
CLDND2
CMTM5
CMTM7
CYB5R3
CYBC1
CYP4F2
DIABLO
EBP
ECPAS
FATE1
FAXDC2
FETUB
GJB2
GOLM1
GOSR2
GYPB
HSD3B7
IGFBP5
INSIG2
ITGAM
JAGN1
LPCAT2
LRAT
MARCHF5
MFSD5
MGLL
MIEF2
MMP14
MOSPD3
MS4A1
NAPB
NAT8
NRM
ORMDL3
PBX3
PLIN3
PLN
PLP2
PNLIPRP1
PTPN9
RABAC1
REEP6
RHOU
RPRM
RUSF1
SACM1L
SCAMP5
SCARF1
SCD
SEC22B
SERP1
SFT2D2
SFXN1
SFXN2
SFXN3
SLC25A46
SLC30A3
SLC35B4
SLC35E4
SMIM1
SNORC
SPG21
ST6GAL2
STRIT1
STX5
STX7
TBRG4
TF
THSD7A
TIMM23
TIMMDC1
TMEM100
TMEM120A
TMEM140
TMEM14C
TMEM167B
TMEM19
TMEM203
TMEM222
TMEM229B
TMEM243
TMEM255B
TMEM31
TMEM42
TMEM60
TMEM86B
TMEM97
TMX2
TPRG1
TREX1
UBXN8
UNC50
VAMP2
VAPA
VAPB
YIPF2
YIPF4
63 interacting genes:
AQP6
AQP9
BCL2L13
BIK
BSCL2
BTN2A1
CD200R1
CD53
CD74
CLEC14A
CLEC2D
CLRN1
CREB3
CXCR3
CYSRT1
ERGIC3
FAM209A
FCGR1A
FCGRT
FKBP7
FNDC9
GGT7
GJA8
GORAB
GPR161
GPX8
HSD17B13
ICAM3
IFNGR2
IL3RA
KEL
KIR2DL3
KRT31
KRT34
LAPTM5
LRRC25
LRRC4C
MFF
MS4A14
MS4A4A
MUC1
PDZK1IP1
PKD2L1
PLEKHB2
PVR
SAR1A
SCARB2
SGPL1
SLAMF6
SLC10A1
SLC35C2
SPACA1
SRPK2
STOM
STOML3
SUSD3
SYNE4
TM4SF18
TMEM106C
TMEM248
TMEM52B
TMEM80
TNFSF14
Entrez ID
345275
149461
HPRD ID
18023
10834
Ensembl ID
ENSG00000170509
ENSG00000164007
Uniprot IDs
Q7Z5P4
Q8N6F1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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