CLDN19 and GGT7

Data Source:
BioGRID (two hybrid)

		CLDN19	GGT7
Description		claudin 19	gamma-glutamyltransferase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Junction Complex Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Identical Protein Binding	Peptidyltransferase Activity Protein Binding Glutathione Hydrolase Activity Hypoglycin A Gamma-glutamyl Transpeptidase Activity Leukotriene C4 Gamma-glutamyl Transferase Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Response To Stimulus Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Regulation Of Transepithelial Transport Positive Regulation Of Cell Junction Assembly	Translation Proteolysis Glutathione Biosynthetic Process Glutathione Catabolic Process Spermatogenesis Protein Phosphopantetheinylation Response To Estradiol Response To Lipopolysaccharide Response To Tumor Necrosis Factor Leukotriene D4 Biosynthetic Process Negative Regulation Of Response To Oxidative Stress
Pathways		Tight junction interactions	Glutathione synthesis and recycling Aflatoxin activation and detoxification
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Coronary artery disease ( 29212778) Estimated glomerular filtration rate ( 31451708) Fish- and plant-related diet ( 32066663) Reticulocyte fraction of red cells ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35C2 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14	13 interacting genes: CLDN19 CMTM7 CYB561 GPR25 HTR4 LHFPL5 LNPEP MALL MTNR1B SLC35A4 TLCD3A TMEM242 TSPO2
Entrez ID		149461	2686
HPRD ID		10834	07488
Ensembl ID		ENSG00000164007	ENSG00000131067
Uniprot IDs		Q8N6F1	A0PJJ9 Q9UJ14
PDB IDs
Enriched GO Terms of Interacting Partners?
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