CLDN19 and MFF

Data Source:
BioGRID (two hybrid)

		CLDN19	MFF
Description		claudin 19	mitochondrial fission factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Junction Complex Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Outer Membrane Peroxisome Synaptic Vesicle Integral Component Of Mitochondrial Outer Membrane Integral Component Of Mitochondrial Membrane Protein-containing Complex
	Molecular Function	Structural Molecule Activity Identical Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Response To Stimulus Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Regulation Of Transepithelial Transport Positive Regulation Of Cell Junction Assembly	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Mitochondrial Fragmentation Involved In Apoptotic Process Mitochondrion Morphogenesis Positive Regulation Of Mitochondrial Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Targeting To Membrane Regulation Of Peroxisome Organization
Pathways		Tight junction interactions
Drugs
Diseases
GWAS			Intraocular pressure ( 29617998) Refractive astigmatism ( 30306274)
Interacting Genes		63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35C2 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14	105 interacting genes: ADIPOQ AGPAT4 AIG1 ANKRD46 APOD APOL2 AQP3 AQP6 ATP6V0B BET1 C14orf180 C1QL4 C3orf52 CD79A CDIPT CEND1 CLDN19 CMTM5 CNIH1 COL4A5 CTXN3 CXCL16 CYB5B CYBC1 DNM1L ERGIC3 FAM209A FAM210B FAM3C FATE1 FCER1G FDCSP FXYD6 GJB1 GKN1 GOSR2 GPR152 IGFBP5 JAGN1 LAT LHFPL5 LPAR3 MEOX2 MIP MMGT1 MOSPD3 MPZL1 MTNR1B NIPAL3 NRM NTS OPN1SW OPRM1 PLK3 PLLP PLN PLP1 RAET1L RETREG3 RHBDL1 SACM1L SEC11C SEC22A SEC22B SEC23A SERINC2 SHISAL1 SLC18A3 SLC35B1 SLC41A2 SLC7A1 SLC7A14 SLC7A8 SMIM1 STRIT1 STX7 STX8 TEX264 TFRC TM6SF1 TMEM128 TMEM140 TMEM14C TMEM201 TMEM218 TMEM229B TMEM237 TMEM254 TMEM42 TMEM60 TMEM86B TMEM88 TMEM97 TMX2 TRAF3IP3 TRAM1L1 TRARG1 TSPAN2 TSPAN33 TSPO2 UNC50 UNC93B1 UPK1B VAMP4 ZFPL1
Entrez ID		149461	56947
HPRD ID		10834	16653
Ensembl ID		ENSG00000164007	ENSG00000168958
Uniprot IDs		Q8N6F1	A0A0A0MS29 A1MAC2 Q9GZY8
PDB IDs
Enriched GO Terms of Interacting Partners?
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