CLDN19 and FKBP7

Data Source:
BioGRID (two hybrid)

		CLDN19	FKBP7
Description		claudin 19	FKBP prolyl isomerase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Junction Complex Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Structural Molecule Activity Identical Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Response To Stimulus Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Regulation Of Transepithelial Transport Positive Regulation Of Cell Junction Assembly	Protein Peptidyl-prolyl Isomerization Peptidyl-proline Modification
Pathways		Tight junction interactions
Drugs
Diseases
GWAS			Atrial fibrillation ( 30061737) Blood protein levels ( 30072576 29875488) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35C2 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14	76 interacting genes: ABHD16A ADIPOQ AP1M1 APOD ASPH BMP10 BRICD5 CDIPT CERCAM CIAO2A CLCA4 CLDN19 CTSA CXCL16 DIABLO FAM3C FARS2 GET3 H4C7 HHATL HSBP1L1 IER3 IFITM3 IRF2 JOSD2 LAT MAN2B2 MIEF2 MRM1 NFU1 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PEX19 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RPRM RUSF1 SGTA SLC38A7 SLC7A14 SNX1 SNX12 STX7 STX8 SUCLA2 TARS2 TCP11X2 THAP4 THSD7B TMEM108 TMEM120B TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TTPA TXNDC12 UBIAD1 UBQLN4 UPK1B VSTM4 WFDC2 WIPI2 YIPF6 ZFPL1
Entrez ID		149461	51661
HPRD ID		10834	08451
Ensembl ID		ENSG00000164007	ENSG00000079150
Uniprot IDs		Q8N6F1	Q9Y680
PDB IDs
Enriched GO Terms of Interacting Partners?
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