IFIT3 and IFIT5

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		IFIT3	IFIT5
Description		interferon induced protein with tetratricopeptide repeats 3	interferon induced protein with tetratricopeptide repeats 5
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Cytosol Plasma Membrane IkappaB Kinase Complex Actin Cytoskeleton Ruffle Membrane Apical Part Of Cell
	Molecular Function	Molecular_function RNA Binding Protein Binding Identical Protein Binding	TRNA Binding RNA Cap Binding Double-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Response To Virus Cellular Response To Interferon-alpha Negative Regulation Of Apoptotic Process Defense Response To Virus Type I Interferon Signaling Pathway	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus
Pathways		Interferon alpha/beta signaling	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Hormone measurements ( 30576415)
Interacting Genes		20 interacting genes: A2M APOE CYP2C8 DEUP1 ECSIT FANCA HAUS1 IFIT1 IFIT1B IFIT2 IFIT5 LONP1 LVRN MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM1 TPM3	17 interacting genes: A2M APOE CDC37 CHUK ECSIT IFIT1 IFIT3 IKBKG LONP1 MAST1 PRDX2 PSEN2 RAD23A RNF32 SARAF SRPK1 SRPK2
Entrez ID		3437	24138
HPRD ID		05228	17130
Ensembl ID		ENSG00000119917	ENSG00000152778
Uniprot IDs		O14879 Q5T765	Q13325
PDB IDs		6C6K	3ZGQ 4HOQ 4HOR 4HOS 4HOT 4J0U
Enriched GO Terms of Interacting Partners?
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