IFIT3 and LONP1

Data Source:
BioGRID (two hybrid)

		IFIT3	LONP1
Description		interferon induced protein with tetratricopeptide repeats 3	lon peptidase 1, mitochondrial
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Mitochondrial Nucleoid
	Molecular Function	Molecular_function RNA Binding Protein Binding Identical Protein Binding	Mitochondrial Promoter Sequence-specific DNA Binding Single-stranded DNA Binding Single-stranded RNA Binding ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding ATP Binding ATPase Activity Identical Protein Binding ADP Binding Sequence-specific DNA Binding G-quadruplex DNA Binding DNA Polymerase Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Response To Virus Cellular Response To Interferon-alpha Negative Regulation Of Apoptotic Process Defense Response To Virus Type I Interferon Signaling Pathway	Mitochondrial Genome Maintenance Response To Hypoxia Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Mitochondrion Organization Aging Response To Hormone Response To Aluminum Ion Mitochondrial DNA Metabolic Process Cellular Response To Oxidative Stress Chaperone-mediated Protein Complex Assembly Proteolysis Involved In Cellular Protein Catabolic Process Oxidation-dependent Protein Catabolic Process
Pathways		Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Hormone measurements ( 30576415)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		20 interacting genes: A2M APOE CYP2C8 DEUP1 ECSIT FANCA HAUS1 IFIT1 IFIT1B IFIT2 IFIT5 LONP1 LVRN MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM1 TPM3	11 interacting genes: A2M APOE CDC37 CDC42 CYP2C8 ECSIT IFIT3 IFIT5 LOXL4 MAST1 RNF32
Entrez ID		3437	9361
HPRD ID		05228	05689
Ensembl ID		ENSG00000119917	ENSG00000196365
Uniprot IDs		O14879 Q5T765	P36776
PDB IDs		6C6K	2X36
Enriched GO Terms of Interacting Partners?
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