FHL1 and ZBTB40

Data Source:
BioGRID (two hybrid)

		FHL1	ZBTB40
Description		four and a half LIM domains 1	zinc finger and BTB domain containing 40
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion	Nucleus
	Molecular Function	Molecular_function Protein Binding Ion Channel Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Molecular_function Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Membrane Depolarization Muscle Organ Development Animal Organ Morphogenesis Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Potassium Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Bone Mineralization
Pathways
Drugs
Diseases		X-linked myopathy with postural muscle atrophy (XMPMA) Reducing body myopathy (RBM) Scapuloperoneal myopathy (SPM) Emery-Dreifuss muscular dystrophy
GWAS			Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Birth weight ( 27680694) Bone mineral density ( 21533022 24249740) Bone mineral density (hip) ( 19801982 18445777) Bone mineral density (spine) ( 19801982 18445777) Bone mineral density (total hip) ( 29883787) Dupuytren's disease ( 28886342) Endometriosis ( 23472165) Femoral neck bone mineral density ( 29499414 22504420) Heel bone mineral density ( 30598549 28869591) Lumbar spine bone mineral density ( 29499414) Lumbar spine bone mineral density (integral) ( 27476799) Lumbar spine bone mineral density (trabecular) ( 27476799) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Medication use (drugs affecting bone structure and mineralization) ( 31015401)
Interacting Genes		32 interacting genes: AKAP12 CBX4 CDC25C CHEK2 CLMN CSRP3 DBN1 DEAF1 DOCK9 EED ENO1 FHL2 HES1 HIVEP3 IGFBP5 LAMA4 MACF1 MYBPC1 NFIL3 PAX7 PDE4DIP PDLIM3 PRNP RBPJ RING1 SRF SRPK1 TTN TXNIP USP15 YWHAE ZBTB40	1 interacting genes: FHL1
Entrez ID		2273	9923
HPRD ID		02157	11086
Ensembl ID		ENSG00000022267	ENSG00000184677
Uniprot IDs		B7Z9A1 Q13642 Q5JXI2	B3KR52 F8WAI8 Q1RMZ5 Q9NUA8
PDB IDs		1X63 2CUP 2CUR 2EGQ
Enriched GO Terms of Interacting Partners?
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