FHL1 and HIVEP3

Data Source:
BioGRID (affinity chromatography technology, two hybrid, pull down)
HPRD (two hybrid, in vitro, in vivo)

		FHL1	HIVEP3
Description		four and a half LIM domains 1	HIVEP zinc finger 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion	Nucleus Cytoplasm
	Molecular Function	Molecular_function Protein Binding Ion Channel Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	Regulation Of Membrane Depolarization Muscle Organ Development Animal Organ Morphogenesis Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Potassium Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways			Regulation of RUNX2 expression and activity
Drugs
Diseases		X-linked myopathy with postural muscle atrophy (XMPMA) Reducing body myopathy (RBM) Scapuloperoneal myopathy (SPM) Emery-Dreifuss muscular dystrophy
GWAS			Adult body size ( 32376654) Airway imaging phenotypes ( 26030696) Breast cancer ( 29059683) Bronchopulmonary dysplasia ( 23897914) Diastolic blood pressure ( 27618452) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) General risk tolerance (MTAG) ( 30643258) Gut microbiota (functional units) ( 27694959) Heel bone mineral density ( 30598549) High myopia ( 32428537) Intraocular pressure ( 29235454) Left ventricular obstructive tract defect (maternal effect) ( 28468790) Lupus nephritis in systemic lupus erythematosus ( 24925725) Neutrophil count ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Night sleep phenotypes ( 27126917) Pulse pressure ( 27841878 30578418) Refractive error ( 32231278) Spatial memory ( 31596458) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Squamous cell lung carcinoma ( 28604730) Sum eosinophil basophil counts ( 27863252) Systolic blood pressure ( 27841878 27618452 30578418) Treatment resistant depression ( 30468137) White blood cell count ( 32888494)
Interacting Genes		32 interacting genes: AKAP12 CBX4 CDC25C CHEK2 CLMN CSRP3 DBN1 DEAF1 DOCK9 EED ENO1 FHL2 HES1 HIVEP3 IGFBP5 LAMA4 MACF1 MYBPC1 NFIL3 PAX7 PDE4DIP PDLIM3 PRNP RBPJ RING1 SRF SRPK1 TTN TXNIP USP15 YWHAE ZBTB40	5 interacting genes: FHL1 RUNX2 TNFRSF1B TRAF1 TRAF2
Entrez ID		2273	59269
HPRD ID		02157	09442
Ensembl ID		ENSG00000022267	ENSG00000127124
Uniprot IDs		B7Z9A1 Q13642 Q5JXI2	Q5T1R4
PDB IDs		1X63 2CUP 2CUR 2EGQ
Enriched GO Terms of Interacting Partners?
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