FHL1 and DOCK9

Data Source:
BioGRID (two hybrid)

		FHL1	DOCK9
Description		four and a half LIM domains 1	dedicator of cytokinesis 9
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion	Cytosol Endomembrane System Membrane
	Molecular Function	Molecular_function Protein Binding Ion Channel Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Cadherin Binding
	Biological Process	Regulation Of Membrane Depolarization Muscle Organ Development Animal Organ Morphogenesis Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Potassium Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Small GTPase Mediated Signal Transduction Blood Coagulation Biological_process Positive Regulation Of GTPase Activity
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases		X-linked myopathy with postural muscle atrophy (XMPMA) Reducing body myopathy (RBM) Scapuloperoneal myopathy (SPM) Emery-Dreifuss muscular dystrophy
GWAS			Asthma (childhood onset) ( 31036433) Blood urea nitrogen levels ( 31152163 29403010) Corneal astigmatism ( 30306274) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Lung function (FEV1/FVC) ( 30804560) Nonsyndromic cleft palate ( 31609978) Platelet distribution width ( 32888494) QRS interval (sulfonylurea treatment interaction) ( 27958378) Refractive error ( 32231278) White blood cell count ( 32888494)
Interacting Genes		32 interacting genes: AKAP12 CBX4 CDC25C CHEK2 CLMN CSRP3 DBN1 DEAF1 DOCK9 EED ENO1 FHL2 HES1 HIVEP3 IGFBP5 LAMA4 MACF1 MYBPC1 NFIL3 PAX7 PDE4DIP PDLIM3 PRNP RBPJ RING1 SRF SRPK1 TTN TXNIP USP15 YWHAE ZBTB40	11 interacting genes: ATG12 CDC42 CLK1 FHL1 LNX1 MYOT NEDD9 NUCKS1 PPP2R5E SNAPIN TAF1
Entrez ID		2273	23348
HPRD ID		02157	09542
Ensembl ID		ENSG00000022267	ENSG00000088387
Uniprot IDs		B7Z9A1 Q13642 Q5JXI2	A0A0A0MT38 A6H8Z6 B3KXE2 B7Z2G6 B9EG73 Q9BZ29
PDB IDs		1X63 2CUP 2CUR 2EGQ	1WG7 2WM9 2WMN 2WMO
Enriched GO Terms of Interacting Partners?
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