SYNE4 and CLDN8

Data Source:
BioGRID (two hybrid)

		SYNE4	CLDN8
Description		spectrin repeat containing nuclear envelope family member 4	claudin 8
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Endoplasmic Reticulum Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS			Response to statin therapy ( 20339536)
Interacting Genes		56 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250 ZNF648	12 interacting genes: ADAM32 ARL13B CLEC17A ERGIC3 KASH5 OPRM1 PKMYT1 SMIM3 SYNE4 TJP1 TMEM80 TRARG1
Entrez ID		163183	9073
HPRD ID		08776	10835
Ensembl ID		ENSG00000181392	ENSG00000156284
Uniprot IDs		Q8N205	A0A0K0K1I9 P56748
PDB IDs		6R16
Enriched GO Terms of Interacting Partners?
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