SYNE4 and TSPAN15

Data Source:
BioGRID (two hybrid)

		SYNE4	TSPAN15
Description		spectrin repeat containing nuclear envelope family member 4	tetraspanin 15
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex	Endoplasmic Reticulum Lumen Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Nuclear Body Cell Junction Late Endosome Membrane Intracellular Membrane-bounded Organelle Tetraspanin-enriched Microdomain
	Molecular Function	Protein Binding	Protein Binding Enzyme Binding
	Biological Process	Establishment Of Epithelial Cell Apical/basal Polarity	Regulation Of Notch Signaling Pathway Cellular Protein Metabolic Process Negative Regulation Of Notch Signaling Pathway Protein Maturation Protein Localization To Plasma Membrane
Pathways			Amyloid fiber formation
Drugs
Diseases
GWAS			Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Response to taxane treatment (placlitaxel) ( 23006423) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thrombosis ( 26908601) Type 2 diabetes ( 32499647) Venous thromboembolism ( 25772935 28373160 31420334 31676865)
Interacting Genes		56 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B IGFBP5 ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 PLPP6 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TCEA2 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250 ZNF648	5 interacting genes: BTRC GYPC RGS2 STRIT1 SYNE4
Entrez ID		163183	23555
HPRD ID		08776	15511
Ensembl ID		ENSG00000181392	ENSG00000099282
Uniprot IDs		Q8N205	O95858
PDB IDs		6R16
Enriched GO Terms of Interacting Partners?
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