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SYNE4 and SENP2
Data Source:
BioGRID
(two hybrid)
SYNE4
SENP2
Description
spectrin repeat containing nuclear envelope family member 4
SUMO specific peptidase 2
Image
GO Annotations
Cellular Component
Integral Component Of Nuclear Outer Membrane
Meiotic Nuclear Membrane Microtubule Tethering Complex
Nucleus
Nuclear Pore
Nucleoplasm
Cytosol
PML Body
Nuclear Membrane
Molecular Function
Protein Binding
Protein Binding
SUMO-specific Protease Activity
Protein Domain Specific Binding
SUMO-specific Endopeptidase Activity
SUMO-specific Isopeptidase Activity
Biological Process
Establishment Of Epithelial Cell Apical/basal Polarity
Positive Regulation Of Protein Phosphorylation
Heart Development
Dorsal/ventral Axis Specification
Protein Transport
Wnt Signaling Pathway
Protein Sumoylation
Protein Desumoylation
Regulation Of Wnt Signaling Pathway
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Protein Destabilization
Negative Regulation Of Protein Binding
Regulation Of DNA Endoreduplication
Negative Regulation Of Chromatin Binding
Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
MRNA Transport
Trophoblast Giant Cell Differentiation
Labyrinthine Layer Development
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
SUMO is proteolytically processed
Drugs
Diseases
GWAS
Diastolic blood pressure (
28135244
27841878
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Estimated glomerular filtration rate (
31152163
31015462
)
Height (
28552196
)
Hip circumference (
28552196
)
JT interval (
29874175
)
PR interval (
30046033
32439900
)
QRS duration (
30012220
)
Seborrheic dermatitis (
29203360
)
Systolic blood pressure (
27841878
26969751
)
Interacting Genes
56 interacting genes:
ABT1
ADIPOQ
BRICD5
C3orf52
CD47
CEP19
CLDN19
CLDN7
CLDN8
CLEC7A
CMTM5
CSGALNACT2
CSNK2B
CXCL9
DEFB121
ECE2
EDDM3B
EMP1
ENTPD3
FAM241B
FATE1
GADD45A
GSK3B
IGFBP5
ITM2B
KLHL12
KLRG1
KTN1
MALL
MARCHF2
NAGK
OCLN
OLFM4
OSTCP1
PAQR5
PLPP6
RIPPLY2
RPS6KA6
SEC22A
SEC23B
SENP2
SFTPC
SLN
SMCO4
TCEA2
TMEM115
TMEM140
TMEM147
TMEM182
TMEM248
TMPRSS4
TRIM69
TSPAN15
VTI1B
ZNF250
ZNF648
38 interacting genes:
ACSF2
AGTRAP
APOC2
APOC4
APP
ARL6IP1
ARMC12
AXIN1
CDCA5
CDK5RAP2
DAXX
ERCC6
FUNDC1
FZR1
HCCS
IKBKG
KASH5
KPNA1
KPNB1
LMNA
MYC
NACC1
NEDD4L
NUP153
PML
RANGAP1
RETREG3
RPRM
SDR16C5
STK38
SUMO1
SUMO2
SUMO3
SYNE4
TMEM239
TNFRSF10D
TPD52
TRIM63
Entrez ID
163183
59343
HPRD ID
08776
07002
Ensembl ID
ENSG00000181392
ENSG00000163904
Uniprot IDs
Q8N205
Q9HC62
PDB IDs
6R16
1TGZ
1TH0
2IO0
2IO1
2IO2
2IO3
3ZO5
5AEK
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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