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TRIM69 and ASNS
Data Source:
BioGRID
(two hybrid, two hybrid)
TRIM69
ASNS
Description
tripartite motif containing 69
asparagine synthetase (glutamine-hydrolyzing)
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Nuclear Speck
Cytosol
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Asparagine Synthase (glutamine-hydrolyzing) Activity
Protein Binding
ATP Binding
Identical Protein Binding
Biological Process
Protein Polyubiquitination
Apoptotic Process
Protein Ubiquitination
Liver Development
Asparagine Biosynthetic Process
Glutamine Metabolic Process
Cellular Amino Acid Biosynthetic Process
Response To Light Stimulus
Response To Mechanical Stimulus
Response To Toxic Substance
Response To Methotrexate
Response To Follicle-stimulating Hormone
Cellular Response To Hormone Stimulus
PERK-mediated Unfolded Protein Response
Cellular Response To Glucose Starvation
Negative Regulation Of Apoptotic Process
Response To Amino Acid
Positive Regulation Of Mitotic Cell Cycle
L-asparagine Biosynthetic Process
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
ATF4 activates genes in response to endoplasmic reticulum stress
Aspartate and asparagine metabolism
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Aspartic acid
Glutamic acid
ATP
Asparagine
Diseases
GWAS
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Regular attendance at a religious group (
29970889
)
Tuberculosis (
30713548
)
Interacting Genes
53 interacting genes:
AIFM2
APP
ASNS
ATP5MC1
BEX2
BIN3
C4orf45
CDSN
DVL1
ETFDH
FAM110A
FAM161A
FAM90A1
FKBP1B
GEM
HAUS1
HGS
IYD
KLHL38
KRT17
LARP1B
LYSMD1
MAGEA4
MAJIN
MED20
MID2
NEK8
NTAQ1
PML
POLR3K
PPP1R18
RECK
RINT1
RSPH14
SF1
SF3A3
SKIL
STMN3
SYCE2
SYNE4
TNNT2
TRIM44
TRIM54
TRIM55
TRIM63
UBE2D1
UBE2D3
UBE2E1
UBE2H
UBE2N
WASHC1
WWOX
ZNF483
5 interacting genes:
ATXN1
STRN4
SUMO2
TRIM69
WDR27
Entrez ID
140691
440
HPRD ID
11518
00153
Ensembl ID
ENSG00000185880
ENSG00000070669
Uniprot IDs
H0YL66
Q86WT6
P08243
PDB IDs
4NQJ
6YXE
6GQ3
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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