TRIM69 and POLR3K

Data Source:
BioGRID (two hybrid)

		TRIM69	POLR3K
Description		tripartite motif containing 69	RNA polymerase III subunit K
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Nucleoplasm RNA Polymerase III Complex Nucleolus Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination	Transcription By RNA Polymerase III Termination Of RNA Polymerase III Transcription Positive Regulation Of Type I Interferon Production TRNA 3'-trailer Cleavage Innate Immune Response Defense Response To Virus
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Body mass index ( 26426971) Mean corpuscular volume ( 32888494) Red blood cell traits ( 23446634)
Interacting Genes		53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483	3 interacting genes: CENPP SDCBP TRIM69
Entrez ID		140691	51728
HPRD ID		11518	16187
Ensembl ID		ENSG00000185880	ENSG00000161980
Uniprot IDs		H0YL66 Q86WT6	Q9Y2Y1
PDB IDs		4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
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