ASNS and STRN4

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASNS	STRN4
Description		asparagine synthetase (glutamine-hydrolyzing)	striatin 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytoplasm Membrane Dendrite Dendritic Spine FAR/SIN/STRIPAK Complex
	Molecular Function	Asparagine Synthase (glutamine-hydrolyzing) Activity Protein Binding ATP Binding Identical Protein Binding	Protein Binding Calmodulin Binding Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Liver Development Asparagine Biosynthetic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Response To Light Stimulus Response To Mechanical Stimulus Response To Toxic Substance Response To Methotrexate Response To Follicle-stimulating Hormone Cellular Response To Hormone Stimulus PERK-mediated Unfolded Protein Response Cellular Response To Glucose Starvation Negative Regulation Of Apoptotic Process Response To Amino Acid Positive Regulation Of Mitotic Cell Cycle L-asparagine Biosynthetic Process	Biological_process
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress Aspartate and asparagine metabolism Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency
Drugs		Aspartic acid Glutamic acid ATP Asparagine
Diseases
GWAS		Regular attendance at a religious group ( 29970889) Tuberculosis ( 30713548)	Chronic lymphocytic leukemia ( 18758461 28165464) Primary sclerosing cholangitis ( 23603763)
Interacting Genes		5 interacting genes: ATXN1 STRN4 SUMO2 TRIM69 WDR27	23 interacting genes: AK5 ASNS CALM1 CAV1 CLDN12 CRK DDX39B DFFA ECSIT GDF9 JUN KLHDC2 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PLPPR3 PPBP SLC25A6 WIPI2 WNT7A
Entrez ID		440	29888
HPRD ID		00153	18125
Ensembl ID		ENSG00000070669	ENSG00000090372
Uniprot IDs		P08243	B3KPF6 Q59GV6 Q9NRL3
PDB IDs		6GQ3
Enriched GO Terms of Interacting Partners?
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