FRA10AC1 and CHERP

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		FRA10AC1	CHERP
Description		FRA10A associated CGG repeat 1	calcium homeostasis endoplasmic reticulum protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phosphatase Activity	RNA Binding Protein Binding Ion Channel Binding
	Biological Process	Dephosphorylation	MRNA Splicing, Via Spliceosome Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321) Refractive error ( 32231278)
Interacting Genes		28 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D ESS2 GATD3A GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 MOB2 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830	48 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAGED1 MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 U2AF2 USP54 WBP4
Entrez ID		118924	10523
HPRD ID		12319	13051
Ensembl ID		ENSG00000148690	ENSG00000085872
Uniprot IDs		Q70Z53	Q8IWX8
PDB IDs
Enriched GO Terms of Interacting Partners?
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