CHERP and U2AF1

Data Source:
BioGRID (two hybrid)

		CHERP	U2AF1
Description		calcium homeostasis endoplasmic reticulum protein	U2 small nuclear RNA auxiliary factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF Complex
	Molecular Function	RNA Binding Protein Binding Ion Channel Binding	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Blood and toenail selenium levels ( 25343990)
Interacting Genes		48 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAGED1 MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 U2AF2 USP54 WBP4	51 interacting genes: AP1B1 AP2B1 CARNMT1 CHERP CIR1 CLK2 DHX38 EFHC2 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 KRT1 KRT75 MAP1B MEOX2 MFAP1 MLH1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A PTEN RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRNP35 SNRPD1 SRPK1 SRRM4 SRSF1 SRSF2 SRSF3 SUV39H1 TOE1 TRA2B U2AF2 VEGFA ZCCHC10 ZNF417 ZRANB2 ZRSR2
Entrez ID		10523	7307
HPRD ID		13051	01871
Ensembl ID		ENSG00000085872	ENSG00000160201
Uniprot IDs		Q8IWX8	P0DN76 Q01081 Q7Z780
PDB IDs			1JMT
Enriched GO Terms of Interacting Partners?
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