FRA10AC1 and CWC27

Data Source:
BioGRID (two hybrid)

		FRA10AC1	CWC27
Description		FRA10A associated CGG repeat 1	CWC27 spliceosome associated cyclophilin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Phosphatase Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Cyclosporin A Binding
	Biological Process	Dephosphorylation	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321) Refractive error ( 32231278)	Adult body size ( 32376654) Bladder cancer ( 27206850) Central corneal thickness ( 31798171 29760442) Diverticular disease ( 30177863) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Obesity-related traits ( 23251661) Refractive error ( 32231278) Systolic blood pressure ( 30224653) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)
Interacting Genes		28 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D ESS2 GATD3A GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 MOB2 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830	4 interacting genes: CLK1 FRA10AC1 HMGA1 MORF4L1
Entrez ID		118924	10283
HPRD ID		12319	11541
Ensembl ID		ENSG00000148690	ENSG00000153015
Uniprot IDs		Q70Z53	D6REK3 Q6UX04
PDB IDs			2HQ6 4R3E 5Z56 5Z58 6FF4 6FF7 6YVH
Enriched GO Terms of Interacting Partners?
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