SLAMF6 and CLDN19

Data Source:
BioGRID (two hybrid)

		SLAMF6	CLDN19
Description		SLAM family member 6	claudin 19
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Nucleus Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Junction Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Structural Molecule Activity Identical Protein Binding
	Biological Process	Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-17 Production Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response T-helper 17 Cell Lineage Commitment	Positive Regulation Of Protein Phosphorylation Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Response To Stimulus Negative Regulation Of Wound Healing Bicellular Tight Junction Assembly Regulation Of Transepithelial Transport Positive Regulation Of Cell Junction Assembly
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Tight junction interactions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Graves' disease ( 23612905) Multiple sclerosis ( 24076602)
Interacting Genes		11 interacting genes: BRICD5 CLDN19 CXCL14 JAGN1 PTPN11 PTPN6 RABAC1 SH2D1A TMBIM6 TMPPE ZAP70	63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35C2 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14
Entrez ID		114836	149461
HPRD ID		05920	10834
Ensembl ID		ENSG00000162739	ENSG00000164007
Uniprot IDs		B4E1U5 Q96DU3	Q8N6F1
PDB IDs		2IF7
Enriched GO Terms of Interacting Partners?
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