CD300A and TMEM60

Data Source:
BioGRID (two hybrid)

		CD300A	TMEM60
Description		CD300a molecule	transmembrane protein 60
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Integral Component Of Membrane
	Molecular Function	Phosphatidylserine Binding Transmembrane Signaling Receptor Activity Protein Binding Phosphatidylethanolamine Binding Signaling Receptor Activity	Protein Binding
	Biological Process	Cell Adhesion Negative Regulation Of B Cell Proliferation Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Mast Cell Degranulation Neutrophil Degranulation Negative Regulation Of MAP Kinase Activity Negative Regulation Of Fibroblast Proliferation Regulation Of Immune Response Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of NK T Cell Activation Negative Regulation Of Phagocytosis, Engulfment Negative Regulation Of Neutrophil Activation Negative Regulation Of Eosinophil Activation Negative Regulation Of Activation Of Janus Kinase Activity Negative Regulation Of Eosinophil Migration
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Neurological blood protein biomarker levels ( 31320639)	Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199)
Interacting Genes		6 interacting genes: KRT38 KRTAP10-3 SEC22A TMEM199 TMEM218 TMEM60	89 interacting genes: AMIGO1 ANKS6 APOL2 AQP2 AQP6 ASGR2 BEST2 BIK BSND CD300A CD53 CD74 CLDN7 CNR2 CPLX4 CYB5R3 EBP EDA ERGIC3 EVI2B FAM209A FFAR2 FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPR42 GPX8 HERPUD2 HIBADH HSD17B13 IFNGR2 KCNK5 KIAA2013 LEUTX LHFPL5 LMNA LRRC3B LRRC59 MFF MGST3 MMD MMGT1 PAGE1 PGRMC2 PI16 REEP2 REEP4 RETREG3 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC13A4 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC30A4 SLC35E3 SLC38A1 SLC39A2 SLC4A1 SLC7A8 SPAG4 SPNS3 SSMEM1 STOM STX1A SYT1 THAP4 TLCD4 TMCO5A TMED9 TMEM139 TMEM14B TMEM203 TMEM237 TMEM45B TMEM52B TMEM86B TMEM9 TMPPE TMPRSS2 TTYH1 VMA21
Entrez ID		11314	85025
HPRD ID		09492	12923
Ensembl ID		ENSG00000167851	ENSG00000135211
Uniprot IDs		J3QKQ4 Q9UGN4	Q9H2L4
PDB IDs		2Q87
Enriched GO Terms of Interacting Partners?
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