CD300A and TMEM218

Data Source:
BioGRID (two hybrid)

		CD300A	TMEM218
Description		CD300a molecule	transmembrane protein 218
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Cilium Integral Component Of Membrane
	Molecular Function	Phosphatidylserine Binding Transmembrane Signaling Receptor Activity Protein Binding Phosphatidylethanolamine Binding Signaling Receptor Activity	Protein Binding
	Biological Process	Cell Adhesion Negative Regulation Of B Cell Proliferation Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Mast Cell Degranulation Neutrophil Degranulation Negative Regulation Of MAP Kinase Activity Negative Regulation Of Fibroblast Proliferation Regulation Of Immune Response Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of NK T Cell Activation Negative Regulation Of Phagocytosis, Engulfment Negative Regulation Of Neutrophil Activation Negative Regulation Of Eosinophil Activation Negative Regulation Of Activation Of Janus Kinase Activity Negative Regulation Of Eosinophil Migration
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Neurological blood protein biomarker levels ( 31320639)	Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)
Interacting Genes		6 interacting genes: KRT38 KRTAP10-3 SEC22A TMEM199 TMEM218 TMEM60	72 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR
Entrez ID		11314	219854
HPRD ID		09492	19054
Ensembl ID		ENSG00000167851	ENSG00000150433
Uniprot IDs		J3QKQ4 Q9UGN4	A2RU14
PDB IDs		2Q87
Enriched GO Terms of Interacting Partners?
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