BCAS2 and ACY1

Data Source:
BioGRID (two hybrid)

		BCAS2	ACY1
Description		BCAS2 pre-mRNA processing factor	aminoacylase 1
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Nucleolus Centrosome Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Aminoacylase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing	Cellular Amino Acid Metabolic Process Xenobiotic Metabolic Process
Pathways		mRNA Splicing - Major Pathway	Aflatoxin activation and detoxification Defective ACY1 causes encephalopathy
Drugs			Aspartic acid Acetylcysteine Copper
Diseases
GWAS		Autism ( 24189344) Chronotype ( 30696823)
Interacting Genes		61 interacting genes: ACY1 AIMP2 BLK C10orf82 C9orf24 CCDC120 CCDC17 ECM1 EMILIN3 ENKD1 EP300 ESR1 ESR2 FAM86C1P GOLGA2 HGS HSF2BP IFI35 IKZF3 KRT20 KRT27 KRT31 KRT34 KRT35 KRT36 KRT37 KRT40 KRT75 KRTAP19-6 KRTAP8-1 LMO1 LMO2 LMO3 LMO4 MED29 MIIP MYOZ3 OIP5 PAX5 PCBD2 PFDN5 PGR PLAGL2 PLEKHF2 POT1 PPARG PPP1R32 SF1 SMARCD1 SNRNP200 SNRPC TCF4 TCHP TP53BP2 TRAF1 TXN2 TXNRD2 UBC USHBP1 YPEL3 ZWINT	12 interacting genes: APP BCAS2 NPM1 NTAQ1 NUDT1 POT1 PRR35 TENT5B TERF1 TLX3 TTC1 WWOX
Entrez ID		10286	95
HPRD ID		05777	00092
Ensembl ID		ENSG00000116752	ENSG00000243989
Uniprot IDs		B2R7W3 O75934	Q03154 V9HWA0
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P	1Q7L
Enriched GO Terms of Interacting Partners?
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