ACY1 and NUDT1

Data Source:
BioGRID (two hybrid)

		ACY1	NUDT1
Description		aminoacylase 1	nudix hydrolase 1
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Acrosomal Vesicle Extracellular Space Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Plasma Membrane Nuclear Membrane
	Molecular Function	Aminoacylase Activity Protein Binding Identical Protein Binding Metal Ion Binding	GTPase Activity Protein Binding 8-oxo-7,8-dihydroguanosine Triphosphate Pyrophosphatase Activity DATP Pyrophosphohydrolase Activity SnoRNA Binding 8-oxo-7,8-dihydrodeoxyguanosine Triphosphate Pyrophosphatase Activity GTP Diphosphatase Activity Metal Ion Binding ATP Diphosphatase Activity M7G(5')pppN Diphosphatase Activity
	Biological Process	Cellular Amino Acid Metabolic Process Xenobiotic Metabolic Process	Purine Nucleotide Catabolic Process DGTP Catabolic Process DNA Repair Response To Oxidative Stress Aging Male Gonad Development Nucleobase-containing Small Molecule Catabolic Process DNA Protection DATP Catabolic Process Response To Cadmium Ion
Pathways		Aflatoxin activation and detoxification Defective ACY1 causes encephalopathy
Drugs		Aspartic acid Acetylcysteine Copper
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Dimensional psychopathology (Social) ( 29496196) Schizophrenia ( 22688191 23974872)
Interacting Genes		12 interacting genes: APP BCAS2 NPM1 NTAQ1 NUDT1 POT1 PRR35 TENT5B TERF1 TLX3 TTC1 WWOX	3 interacting genes: ACY1 FMNL3 TRMT12
Entrez ID		95	4521
HPRD ID		00092	02634
Ensembl ID		ENSG00000243989	ENSG00000106268
Uniprot IDs		Q03154 V9HWA0	A0A024R819 A0A024R858 P36639
PDB IDs		1Q7L	1IRY 3Q93 3WHW 3ZR0 3ZR1 4C9W 4C9X 4N1T 4N1U 5ANS 5ANT 5ANU 5ANV 5ANW 5FSI 5FSK 5FSL 5FSM 5FSN 5FSO 5GHI 5GHJ 5GHM 5GHN 5GHO 5GHP 5GHQ 5NGR 5NGS 5NGT 5NHY 5OTM 5WS7 6AA3 6AA4 6AA5 6EQ2 6EQ3 6EQ4 6EQ5 6EQ6 6EQ7 6F1X 6F20 6F22 6F23 6GLE 6GLF 6GLG 6GLH 6GLI 6GLJ 6GLK 6GLL 6GLM 6GLN 6GLO 6GLP 6GLQ 6GLR 6GLS 6GLT 6GLU 6GLV 6IJY 6ILI 6IMZ 6JVF 6JVG 6JVH 6JVI 6JVJ 6JVK 6JVL 6JVM 6JVN 6JVO 6JVP 6JVQ 6JVR 6JVS 6JVT 6QVO 6US2 6US3 6US4
Enriched GO Terms of Interacting Partners?
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