BCAS2 and IFI35

Data Source:
BioGRID (two hybrid)

		BCAS2	IFI35
Description		BCAS2 pre-mRNA processing factor	interferon induced protein 35
Image			No pdb structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Nucleolus Centrosome Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Extracellular Space Nucleus Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing	Macrophage Activation Involved In Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Type I Interferon Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		mRNA Splicing - Major Pathway	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Autism ( 24189344) Chronotype ( 30696823)	Coronary artery disease ( 29212778)
Interacting Genes		61 interacting genes: ACY1 AIMP2 BLK C10orf82 C9orf24 CCDC120 CCDC17 ECM1 EMILIN3 ENKD1 EP300 ESR1 ESR2 FAM86C1P GOLGA2 HGS HSF2BP IFI35 IKZF3 KRT20 KRT27 KRT31 KRT34 KRT35 KRT36 KRT37 KRT40 KRT75 KRTAP19-6 KRTAP8-1 LMO1 LMO2 LMO3 LMO4 MED29 MIIP MYOZ3 OIP5 PAX5 PCBD2 PFDN5 PGR PLAGL2 PLEKHF2 POT1 PPARG PPP1R32 SF1 SMARCD1 SNRNP200 SNRPC TCF4 TCHP TP53BP2 TRAF1 TXN2 TXNRD2 UBC USHBP1 YPEL3 ZWINT	12 interacting genes: BATF BCAS2 CLEC4G CYTH3 EML2 FHL2 KDM1A MAPK1 NMI PLEKHO1 TRIM55 TRIM63
Entrez ID		10286	3430
HPRD ID		05777	02844
Ensembl ID		ENSG00000116752	ENSG00000068079
Uniprot IDs		B2R7W3 O75934	P80217
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P
Enriched GO Terms of Interacting Partners?
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