BCAS2 and TXNRD2

Data Source:
BioGRID (pull down)

		BCAS2	TXNRD2
Description		BCAS2 pre-mRNA processing factor	thioredoxin reductase 2
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Nucleolus Centrosome Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Thioredoxin-disulfide Reductase Activity Protein Binding Flavin Adenine Dinucleotide Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing	Response To Oxygen Radical Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways		mRNA Splicing - Major Pathway	Detoxification of Reactive Oxygen Species
Drugs			Motexafin gadolinium
Diseases
GWAS		Autism ( 24189344) Chronotype ( 30696823)	Glaucoma ( 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary angle closure) ( 22922875) Glaucoma (primary open-angle) ( 26752265 29891935) Intraocular pressure ( 29785010 31959993 30054594) Lean body mass ( 28552196) Staphylococcus aureus infection ( 24847357)
Interacting Genes		61 interacting genes: ACY1 AIMP2 BLK C10orf82 C9orf24 CCDC120 CCDC17 ECM1 EMILIN3 ENKD1 EP300 ESR1 ESR2 FAM86C1P GOLGA2 HGS HSF2BP IFI35 IKZF3 KRT20 KRT27 KRT31 KRT34 KRT35 KRT36 KRT37 KRT40 KRT75 KRTAP19-6 KRTAP8-1 LMO1 LMO2 LMO3 LMO4 MED29 MIIP MYOZ3 OIP5 PAX5 PCBD2 PFDN5 PGR PLAGL2 PLEKHF2 POT1 PPARG PPP1R32 SF1 SMARCD1 SNRNP200 SNRPC TCF4 TCHP TP53BP2 TRAF1 TXN2 TXNRD2 UBC USHBP1 YPEL3 ZWINT	7 interacting genes: BCAS2 GTF2H1 NCOA2 NCOA6 NCOR1 PSMC3 TADA3
Entrez ID		10286	10587
HPRD ID		05777	18519
Ensembl ID		ENSG00000116752	ENSG00000184470
Uniprot IDs		B2R7W3 O75934	E7EWK1 Q9NNW7
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P	1W1E
Enriched GO Terms of Interacting Partners?
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