IFI35 and BATF

Data Source:
HPRD (two hybrid, in vitro)

		IFI35	BATF
Description		interferon induced protein 35	basic leucine zipper ATF-like transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cytosol Membrane	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Macrophage Activation Involved In Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Type I Interferon Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling	Cytokine Production Lymphoid Progenitor Cell Differentiation Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Cytokine-mediated Signaling Pathway DNA Damage Response, Signal Transduction By P53 Class Mediator Defense Response To Protozoan Myeloid Dendritic Cell Differentiation T-helper 2 Cell Differentiation Isotype Switching Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation T-helper 17 Cell Differentiation T-helper 17 Cell Lineage Commitment
Pathways		Interferon alpha/beta signaling	Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Allergic disease (asthma, hay fever or eczema) ( 29083406) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Multiple sclerosis ( 31604244 24076602 21833088) Rheumatoid arthritis ( 20453842)
Interacting Genes		12 interacting genes: BATF BCAS2 CLEC4G CYTH3 EML2 FHL2 KDM1A MAPK1 NMI PLEKHO1 TRIM55 TRIM63	21 interacting genes: ATF2 ATF3 ATF4 BATF3 CEBPA CEBPE CEBPG COX8A DBP DDIT3 EPAS1 FOS GOPC IFI35 IRF4 JUN JUNB JUND KDM1A NFIL3 SNAPC5
Entrez ID		3430	10538
HPRD ID		02844	09820
Ensembl ID		ENSG00000068079	ENSG00000156127
Uniprot IDs		P80217	Q16520
PDB IDs
Enriched GO Terms of Interacting Partners?
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