PAN2 and RNF144B

Number of citations of the paper that reports this interaction (PubMedID 23105109)
16

Data Source:
BioGRID (two hybrid)

		PAN2	RNF144B
Description		poly(A) specific ribonuclease subunit PAN2	ring finger protein 144B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytosol PAN Complex	Ubiquitin Ligase Complex Cytoplasm Cytosol Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	3'-5'-exoribonuclease Activity Nucleic Acid Binding Poly(A)-specific Ribonuclease Activity Protein Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process
Pathways		Deadenylation of mRNA	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Axial length ( 24144296) Height ( 25429064)	Age at voice drop ( 27182965) Caudal middle frontal gyrus volume ( 31530798) Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Chronotype ( 30696823) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Endometriosis ( 23472165) Facial morphology ( 31763980) General risk tolerance (MTAG) ( 30643258) Pulse pressure ( 30224653) Thiopurine S-methyltransferase activity ( 27770449)
Interacting Genes		7 interacting genes: DYNLL1 PABPC1 PAN3 RBCK1 RNF144B TNRC6A TRIM35	11 interacting genes: CDKN1A PAN2 UBC UBE2I UBE2L3 UBE2L6 UBE2T UBE2U UBE2Z USP15 USP2
Entrez ID		9924	255488
HPRD ID		15640	17126
Ensembl ID		ENSG00000135473	ENSG00000137393
Uniprot IDs		Q504Q3	Q7Z419
PDB IDs
Enriched GO Terms of Interacting Partners?
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