PAN2 and PAN3

Number of citations of the paper that reports this interaction (PubMedID 14583602)
46

Data Source:
HPRD (in vivo, in vitro)

		PAN2	PAN3
Description		poly(A) specific ribonuclease subunit PAN2	poly(A) specific ribonuclease subunit PAN3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytosol PAN Complex	P-body Cytosol PAN Complex
	Molecular Function	3'-5'-exoribonuclease Activity Nucleic Acid Binding Poly(A)-specific Ribonuclease Activity Protein Binding Metal Ion Binding	RNA Binding Poly(A)-specific Ribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly RNA Phosphodiester Bond Hydrolysis, Exonucleolytic	Nuclear-transcribed MRNA Poly(A) Tail Shortening Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Processing Protein Phosphorylation Protein Targeting Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		Deadenylation of mRNA	Deadenylation of mRNA
Drugs
Diseases
GWAS		Axial length ( 24144296) Height ( 25429064)	Bipolar disorder ( 20351715) Body mass index ( 26426971) Granulocyte percentage of myeloid white cells ( 27863252) Hepcidin/transferrin saturation ratio ( 27846281) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Pancreatic cancer ( 25086665)
Interacting Genes		7 interacting genes: DYNLL1 PABPC1 PAN3 RBCK1 RNF144B TNRC6A TRIM35	4 interacting genes: PABPC1 PAN2 SVIL TNRC6B
Entrez ID		9924	255967
HPRD ID		15640	17818
Ensembl ID		ENSG00000135473	ENSG00000152520
Uniprot IDs		Q504Q3	Q58A45
PDB IDs
Enriched GO Terms of Interacting Partners?
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