RNF144B and UBE2L6

Number of citations of the paper that reports this interaction (PubMedID 16427630)
18

Data Source:
HPRD (in vitro)

		RNF144B	UBE2L6
Description		ring finger protein 144B	ubiquitin conjugating enzyme E2 L6
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Cytosol Integral Component Of Membrane Mitochondrial Membrane	Ubiquitin Ligase Complex Nucleoplasm Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding ISG15 Transferase Activity Ubiquitin Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process	Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Translesion Synthesis ISG15-protein Conjugation Negative Regulation Of Type I Interferon Production Cellular Protein Metabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	ISG15 antiviral mechanism DDX58/IFIH1-mediated induction of interferon-alpha/beta Termination of translesion DNA synthesis Negative regulators of DDX58/IFIH1 signaling Negative regulators of DDX58/IFIH1 signaling Amyloid fiber formation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Caudal middle frontal gyrus volume ( 31530798) Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Chronotype ( 30696823) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Endometriosis ( 23472165) Facial morphology ( 31763980) General risk tolerance (MTAG) ( 30643258) Pulse pressure ( 30224653) Thiopurine S-methyltransferase activity ( 27770449)	Blood protein levels ( 28240269)
Interacting Genes		11 interacting genes: CDKN1A PAN2 UBC UBE2I UBE2L3 UBE2L6 UBE2T UBE2U UBE2Z USP15 USP2	38 interacting genes: ARHGDIA ARIH1 ARIH2 CBLC DTX3 FLT3 HERC5 LONRF1 MAP3K1 MUL1 NEDD4L PJA2 PRKN RBCK1 RBX1 RNF122 RNF125 RNF144A RNF144B RNF150 RNF19A RNF216 RNF25 RNF4 RNF40 RUNX1 SIAH1 SIAH2 SPEN TOPORS TRAF7 TRIM25 TRIM27 TRIM8 UBA1 UBA6 UBA7 UBE3A
Entrez ID		255488	9246
HPRD ID		17126	04867
Ensembl ID		ENSG00000137393	ENSG00000156587
Uniprot IDs		Q7Z419	O14933
PDB IDs			1WZV 1WZW 2KJH
Enriched GO Terms of Interacting Partners?
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