GIT2 and KCTD5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GIT2	KCTD5
Description		GIT ArfGAP 2	potassium channel tetramerization domain containing 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Focal Adhesion	Nucleus Cytoplasm Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding Identical Protein Binding Protein-containing Complex Binding Cullin Family Protein Binding
	Biological Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	Viral Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		44 interacting genes: ACTG1 ACTN1 ARHGEF7 ATF5 C4BPA CALCOCO2 CORO1A E2F2 EDC4 GCH1 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG	8 interacting genes: CD1A CUL3 EP300 GIT2 GORASP2 NEK6 NXF1 PRKAB2
Entrez ID		9815	54442
HPRD ID		09779	13768
Ensembl ID		ENSG00000139436	ENSG00000167977
Uniprot IDs		F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58	Q9NXV2
PDB IDs			3DRX 3DRY 3DRZ
Enriched GO Terms of Interacting Partners?
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