KCTD5 and GIT2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		KCTD5	GIT2
Description		potassium channel tetramerization domain containing 5	GIT ArfGAP 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cul3-RING Ubiquitin Ligase Complex	Nucleoplasm Focal Adhesion
	Molecular Function	Protein Binding Identical Protein Binding Protein-containing Complex Binding Cullin Family Protein Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Viral Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Homooligomerization	Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)
Interacting Genes		8 interacting genes: CD1A CUL3 EP300 GIT2 GORASP2 NEK6 NXF1 PRKAB2	44 interacting genes: ACTG1 ACTN1 ARHGEF7 ATF5 C4BPA CALCOCO2 CORO1A E2F2 EDC4 GCH1 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		54442	9815
HPRD ID		13768	09779
Ensembl ID		ENSG00000167977	ENSG00000139436
Uniprot IDs		Q9NXV2	F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58
PDB IDs		3DRX 3DRY 3DRZ
Enriched GO Terms of Interacting Partners?
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