KMT2B and ZNF512B

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
BioGRID (two hybrid)

		KMT2B	ZNF512B
Description		lysine methyltransferase 2B	zinc finger protein 512B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Histone Methyltransferase Complex	Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K4 Specific) Unmethylated CpG Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Ovarian Follicle Development Memory Oocyte Differentiation Gene Silencing Ovulation Histone H3-K4 Dimethylation Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Chromatin-mediated Maintenance Of Transcription Histone H3-K4 Methylation Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation Histone H3-K4 Monomethylation
Pathways		PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS			Birth weight ( 31043758) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)
Interacting Genes		25 interacting genes: ANXA1 ANXA7 ASH2L ATP1B1 ATXN1 CDKN1A GRB7 H3C1 H3C14 MTDH NREP PIK3R3 PIN1 PRPF40A RAP1B RBBP5 RCC1 RPP14 SEPTIN8 SMAD3 SMARCB1 SMN1 TK1 TSC22D1 ZNF512B	60 interacting genes: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2
Entrez ID		9757	57473
HPRD ID		06017	13840
Ensembl ID		ENSG00000272333	ENSG00000196700
Uniprot IDs		Q9UMN6	Q96KM6
PDB IDs		3UVM 4ERZ 4PZI	2GQJ
Enriched GO Terms of Interacting Partners?
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