ZNF512B and DROSHA

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
BioGRID (two hybrid)

		ZNF512B	DROSHA
Description		zinc finger protein 512B	drosha ribonuclease III
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GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nucleolus Postsynaptic Density Microprocessor Complex
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Lipopolysaccharide Binding RNA Binding Double-stranded RNA Binding Ribonuclease III Activity Protein Binding DEAD/H-box RNA Helicase Binding Protein Homodimerization Activity SMAD Binding Metal Ion Binding R-SMAD Binding Primary MiRNA Binding
	Biological Process		RNA Processing MiRNA Metabolic Process Positive Regulation Of Gene Expression RRNA Catabolic Process Production Of SiRNA Involved In RNA Interference Primary MiRNA Processing Pre-miRNA Processing Ribosome Biogenesis Regulation Of Regulatory T Cell Differentiation Regulation Of Inflammatory Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Regulation Of MiRNA Metabolic Process
Pathways			MicroRNA (miRNA) biogenesis
Drugs
Diseases
GWAS		Birth weight ( 31043758) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)	Cerebrospinal fluid t-tau levels in Alzheimer's disease dementia ( 29274321) Lung function (FEV1) ( 26635082) Tuberculosis ( 30713548)
Interacting Genes		60 interacting genes: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2	3 interacting genes: DGCR8 SP1 ZNF512B
Entrez ID		57473	29102
HPRD ID		13840	10196
Ensembl ID		ENSG00000196700	ENSG00000113360
Uniprot IDs		Q96KM6	Q9NRR4
PDB IDs		2GQJ	2KHX 2NA2 5B16
Enriched GO Terms of Interacting Partners?
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