PRC1 and SF3B2

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		PRC1	SF3B2
Description		protein regulator of cytokinesis 1	splicing factor 3b subunit 2
Image
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Spindle Cytosol Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding	RNA Binding Protein Binding
	Biological Process	Mitotic Spindle Elongation Microtubule Bundle Formation Positive Regulation Of Cell Proliferation Regulation Of Cytokinesis Cell Division	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Viral Process
Pathways		RHO GTPases activate CIT	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Breast cancer ( 29059683 25038754) Mean platelet volume ( 27863252) Multisite chronic pain ( 31194737) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 20581827 30718926 28869590)	Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Metabolite levels ( 23823483)
Interacting Genes		25 interacting genes: AKAP9 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 NDEL1 PCM1 PLK1 RACGAP1 RBM10 RPA2 SF3B2 SLAIN1 TRIM37 USHBP1 YWHAE	31 interacting genes: AKAP9 APBB1 APP C7orf25 C8orf33 CASK CSNK2A1 ECPAS ERG FMR1 FRA10AC1 HNRNPC KDM1A LSM2 LSM3 PCBP2 PRC1 PRPF40A RBM10 RBM7 RBM8A SF3B4 SMAD3 SNRNP200 TCERG1 THOC1 TOE1 TOPBP1 TTC14 U2AF1 ZCCHC10
Entrez ID		9055	10992
HPRD ID		17899	10410
Ensembl ID		ENSG00000198901	ENSG00000087365
Uniprot IDs		A0A024RC67 O43663	Q13435
PDB IDs		3NRX 3NRY 4L3I 4L6Y 5KMG	2DO5 5Z56 5Z57 5Z58 6AH0 6FF4 6FF7 6QX9
Enriched GO Terms of Interacting Partners?
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