SF3B2 and TOE1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		SF3B2	TOE1
Description		splicing factor 3b subunit 2	target of EGR1, exonuclease
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	3'-5'-exoribonuclease Activity RNA Binding Poly(A)-specific Ribonuclease Activity Protein Binding SnRNA Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Viral Process	SnRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Metabolite levels ( 23823483)
Interacting Genes		31 interacting genes: AKAP9 APBB1 APP C7orf25 C8orf33 CASK CSNK2A1 ECPAS ERG FMR1 FRA10AC1 HNRNPC KDM1A LSM2 LSM3 PCBP2 PRC1 PRPF40A RBM10 RBM7 RBM8A SF3B4 SMAD3 SNRNP200 TCERG1 THOC1 TOE1 TOPBP1 TTC14 U2AF1 ZCCHC10	25 interacting genes: ABCF3 AGGF1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83
Entrez ID		10992	114034
HPRD ID		10410	18212
Ensembl ID		ENSG00000087365	ENSG00000132773
Uniprot IDs		Q13435	Q96GM8
PDB IDs		2DO5 5Z56 5Z57 5Z58 6AH0 6FF4 6FF7 6QX9	2FC6
Enriched GO Terms of Interacting Partners?
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