PSTPIP1 and MVP

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		PSTPIP1	MVP
Description		proline-serine-threonine phosphatase interacting protein 1	major vault protein
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GO Annotations	Cellular Component	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm	Extracellular Region Nucleus Nuclear Pore Cytoplasm Cytosol Cytoskeleton Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Identical Protein Binding	Protein Binding Protein Kinase Binding Protein Phosphatase Binding Identical Protein Binding
	Biological Process	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response	Protein Transport Regulation Of Signaling Negative Regulation Of Signaling Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway Neutrophil Degranulation MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection	Neutrophil degranulation
Drugs
Diseases		Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Neurofibrillary tangles ( 31497858)
Interacting Genes		42 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 DNM2 EXOC5 FAM90A1 FASLG FBXL18 HMG20A KHDRBS1 LSM4 MEFV MFGE8 MVP NAV2 PCDHB14 PRPF31 PTPN12 PTPN18 RINT1 RTP5 RXRB SDCBP SH2D4A SHBG SPG7 SYCE1 TFIP11 TRAF3IP3 TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZNF175 ZNF688	58 interacting genes: ADAMTSL4 BANP C1orf94 CALCOCO2 CAMK2B CKAP4 DISC1 DLX2 EPHX2 ESR1 GIT2 GOLGA2 HP IHO1 KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MRTFA MT-CYB NNT NOTCH2NLA PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SAXO1 SERTAD1 SKIL SLC2A4 STN1 TCF4 TENT5C TFCP2 TLE5 TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 TSPOAP1 UBC VAC14 ZBTB32 ZMIZ2
Entrez ID		9051	9961
HPRD ID		05891	05475
Ensembl ID		ENSG00000140368	ENSG00000013364
Uniprot IDs		A0A0S2Z5P3 O43586	Q14764 X5D2M8 X5D7K9 X5DNU0
PDB IDs		2DIL	1Y7X
Enriched GO Terms of Interacting Partners?
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